5/24/2025
Last update
5/24/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 19 Reviews
8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%
Top Medical Research Studies
8
We examined how vitamin E affects common cold incidence among different groups. In our study involving over 14,500 participants, we found that older smokers living in cities benefited from vitamin E, showing a 46% reduction in cold risk.
In contrast, those who smoked more and lived in rural areas faced a higher cold risk with vitamin E intake. This suggests that vitamin E's impact can vary greatly based on age, smoking habits, and where one lives, indicating the need for cautious public health guidelines regarding vitamin E supplementation.
In contrast, those who smoked more and lived in rural areas faced a higher cold risk with vitamin E intake. This suggests that vitamin E's impact can vary greatly based on age, smoking habits, and where one lives, indicating the need for cautious public health guidelines regarding vitamin E supplementation.
Read More
7
We aimed to find out if a daily dose of 200 IU of vitamin E could help reduce respiratory tract infections in elderly nursing home residents over a year.
Conducted at 33 care facilities, our study involved 617 participants aged 65 and older, with 451 completing it.
While vitamin E supplementation didn’t significantly reduce lower respiratory infections, we did notice it offered some protection against upper respiratory infections, especially the common cold, suggesting this area is worth exploring further.
Conducted at 33 care facilities, our study involved 617 participants aged 65 and older, with 451 completing it.
While vitamin E supplementation didn’t significantly reduce lower respiratory infections, we did notice it offered some protection against upper respiratory infections, especially the common cold, suggesting this area is worth exploring further.
Read More
4
We explored the impact of vitamin E, along with vitamin C and beta-carotene, on the common cold in a large group of 21,796 male smokers. Over four years, we monitored cold episodes through regular surveys.
Unfortunately, our findings revealed no significant benefit of these vitamins on reducing cold incidence overall. However, for men aged 65 and older, a slight decrease in colds was noted among those taking vitamin E, particularly in those who smoked fewer than 15 cigarettes daily.
Unfortunately, our findings revealed no significant benefit of these vitamins on reducing cold incidence overall. However, for men aged 65 and older, a slight decrease in colds was noted among those taking vitamin E, particularly in those who smoked fewer than 15 cigarettes daily.
Read More
Most Useful Reviews
9
Eased cold symptoms
9 people found this helpful
My blood circulation has long been poor, causing my toes to feel extremely cold in winter, even in a warm room. Since taking megavitamin, that issue has improved. I also realised a lack of vitamin E leads to redness and itchiness in my toes during winter. Thank you for this successful product!
Read More
9
Warm hands and feet
3 people found this helpful
I started taking this as I was worried about having cold hands and feet. Now, my hands are warm all the time, my complexion has improved, and the dullness under my eyes has reduced. I couldn't sleep before due to cold extremities—this supplement is fabulous!
Read More
9
Eases common cold
3 people found this helpful
I noticed my common cold symptoms were lighter after starting vitamin E. My son-in-law caught a cold, and when I gave him E-400, I was impressed by its effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
- All Researches
8
We examined how vitamin E affects common cold incidence among different groups. In our study involving over 14,500 participants, we found that older smokers living in cities benefited from vitamin E, showing a 46% reduction in cold risk.
In contrast, those who smoked more and lived in rural areas faced a higher cold risk with vitamin E intake. This suggests that vitamin E's impact can vary greatly based on age, smoking habits, and where one lives, indicating the need for cautious public health guidelines regarding vitamin E supplementation.
In contrast, those who smoked more and lived in rural areas faced a higher cold risk with vitamin E intake. This suggests that vitamin E's impact can vary greatly based on age, smoking habits, and where one lives, indicating the need for cautious public health guidelines regarding vitamin E supplementation.
Read More
7
We aimed to find out if a daily dose of 200 IU of vitamin E could help reduce respiratory tract infections in elderly nursing home residents over a year.
Conducted at 33 care facilities, our study involved 617 participants aged 65 and older, with 451 completing it.
While vitamin E supplementation didn’t significantly reduce lower respiratory infections, we did notice it offered some protection against upper respiratory infections, especially the common cold, suggesting this area is worth exploring further.
Conducted at 33 care facilities, our study involved 617 participants aged 65 and older, with 451 completing it.
While vitamin E supplementation didn’t significantly reduce lower respiratory infections, we did notice it offered some protection against upper respiratory infections, especially the common cold, suggesting this area is worth exploring further.
Read More
4
We explored the impact of vitamin E, along with vitamin C and beta-carotene, on the common cold in a large group of 21,796 male smokers. Over four years, we monitored cold episodes through regular surveys.
Unfortunately, our findings revealed no significant benefit of these vitamins on reducing cold incidence overall. However, for men aged 65 and older, a slight decrease in colds was noted among those taking vitamin E, particularly in those who smoked fewer than 15 cigarettes daily.
Unfortunately, our findings revealed no significant benefit of these vitamins on reducing cold incidence overall. However, for men aged 65 and older, a slight decrease in colds was noted among those taking vitamin E, particularly in those who smoked fewer than 15 cigarettes daily.
Read More
User Reviews
USERS' SCORE
Good
Based on 19 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eased cold symptoms
9 people found this helpful
My blood circulation has long been poor, causing my toes to feel extremely cold in winter, even in a warm room. Since taking megavitamin, that issue has improved. I also realised a lack of vitamin E leads to redness and itchiness in my toes during winter. Thank you for this successful product!
Read More
9
Warm hands and feet
3 people found this helpful
I started taking this as I was worried about having cold hands and feet. Now, my hands are warm all the time, my complexion has improved, and the dullness under my eyes has reduced. I couldn't sleep before due to cold extremities—this supplement is fabulous!
Read More
9
Eases common cold
3 people found this helpful
I noticed my common cold symptoms were lighter after starting vitamin E. My son-in-law caught a cold, and when I gave him E-400, I was impressed by its effects.
Read More
9
Relieved cold intolerance
1 people found this helpful
This product is great. The cold in my limbs has disappeared completely.
Read More
9
Effective in winter
1 people found this helpful
I was worried about my cold hands and feet, but after starting vitamin E, I've experienced improved circulation and reduced cold symptoms. I find it particularly effective for combating cold during winter.
Read More
Frequently Asked Questions
6
Enhanced blood circulation
Switching from 200 to 400, I found this vitamin E easier to take. Two weeks after I began, I observed a slight improvement in my blood flow, and my neck coldness upon waking has diminished.
7.5
Warmer extremities
1 people found this helpful
After taking vitamin E for 2-3 months, I warm up much quicker. My cold feet persist, but I find I warm up immediately upon entering a warm room. My back and shoulder pain has also improved.
9
Eased cold symptoms
9 people found this helpful
My blood circulation has long been poor, causing my toes to feel extremely cold in winter, even in a warm room. Since taking megavitamin, that issue has improved. I also realised a lack of vitamin E leads to redness and itchiness in my toes during winter. Thank you for this successful product!
9
Warm hands and feet
3 people found this helpful
I started taking this as I was worried about having cold hands and feet. Now, my hands are warm all the time, my complexion has improved, and the dullness under my eyes has reduced. I couldn't sleep before due to cold extremities—this supplement is fabulous!
6
Cold sensitivity relief
4 people found this helpful
Since I began taking one tablet of vitamin E after dinner, I've felt an improvement in my blood circulation. The tablets are small and easy to swallow. I take them hoping to alleviate PMS too, and overall, I believe it's beneficial, especially for those who are sensitive to the cold.
7.5
Improved blood flow
1 people found this helpful
While there are products with mixed tocopherols, I found this d-α tocopherol variant provided a better experience. I believe vitamin E improves blood flow, resulting in warmer hands and feet, particularly during cold weather.
9
Eases common cold
3 people found this helpful
I noticed my common cold symptoms were lighter after starting vitamin E. My son-in-law caught a cold, and when I gave him E-400, I was impressed by its effects.
6
Anti-aging effects
3 people found this helpful
I take this with multivitamins expecting a synergistic effect on skin health and anti-aging. I feel that vitamin E has improved circulation in my peripheral blood vessels, as my sensitivity to cold has noticeably decreased since I began taking it.
7.5
Lighter period pain
1 people found this helpful
I take 2-3 tablets after breakfast. Although I can't determine if it’s solely due to this supplement, my sensitivity to cold has significantly lessened. I’ve also noticed a reduction in my period pain.
9
Supports common cold
1 people found this helpful
E-400 from iHerb has been my preferred vitamin E supplement, and I’m delighted with the results. It supports overall health and skin vitality, and I’ve seen improvements in my skin, nails, and hair. It has also bolstered my immune system during the common cold season.
9
Blood flow improvement
1 people found this helpful
I began taking this based on the Fujikawa theory. Initially, I increased my dosage from one to three; within an hour, I felt blood flow improve in my extremities. This vitamin E enhances circulation, and my cold extremities have improved since taking it.
8
We examined how vitamin E affects common cold incidence among different groups. In our study involving over 14,500 participants, we found that older smokers living in cities benefited from vitamin E, showing a 46% reduction in cold risk.
In contrast, those who smoked more and lived in rural areas faced a higher cold risk with vitamin E intake. This suggests that vitamin E's impact can vary greatly based on age, smoking habits, and where one lives, indicating the need for cautious public health guidelines regarding vitamin E supplementation.
In contrast, those who smoked more and lived in rural areas faced a higher cold risk with vitamin E intake. This suggests that vitamin E's impact can vary greatly based on age, smoking habits, and where one lives, indicating the need for cautious public health guidelines regarding vitamin E supplementation.
7
We aimed to find out if a daily dose of 200 IU of vitamin E could help reduce respiratory tract infections in elderly nursing home residents over a year.
Conducted at 33 care facilities, our study involved 617 participants aged 65 and older, with 451 completing it.
While vitamin E supplementation didn’t significantly reduce lower respiratory infections, we did notice it offered some protection against upper respiratory infections, especially the common cold, suggesting this area is worth exploring further.
Conducted at 33 care facilities, our study involved 617 participants aged 65 and older, with 451 completing it.
While vitamin E supplementation didn’t significantly reduce lower respiratory infections, we did notice it offered some protection against upper respiratory infections, especially the common cold, suggesting this area is worth exploring further.
4
We explored the impact of vitamin E, along with vitamin C and beta-carotene, on the common cold in a large group of 21,796 male smokers. Over four years, we monitored cold episodes through regular surveys.
Unfortunately, our findings revealed no significant benefit of these vitamins on reducing cold incidence overall. However, for men aged 65 and older, a slight decrease in colds was noted among those taking vitamin E, particularly in those who smoked fewer than 15 cigarettes daily.
Unfortunately, our findings revealed no significant benefit of these vitamins on reducing cold incidence overall. However, for men aged 65 and older, a slight decrease in colds was noted among those taking vitamin E, particularly in those who smoked fewer than 15 cigarettes daily.
References
- Hemilä H, Virtamo J, Albanes D, Kaprio J. The effect of vitamin E on common cold incidence is modified by age, smoking and residential neighborhood. J Am Coll Nutr. 2006;25:332.
- Meydani SN, Leka LS, Fine BC, Dallal GE, Keusch GT, et al. Vitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trial. JAMA. 2004;292:828.
- Hemilä H, Kaprio J, Albanes D, Heinonen OP, Virtamo J. Vitamin C, vitamin E, and beta-carotene in relation to common cold incidence in male smokers. Epidemiology. 2002;13:32.
